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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
The types of cancer that alpha interferons are used to treat include hairy cell leukemia, melanoma, follicular non-Hodgkin's lymphoma, and AIDS-related Kaposi's sarcoma.
There are approximately 3 million unintended pregnancies in the United States each year.
Medication errors are more common among seriously ill patients than with those with minor conditions.
The heart is located in the center of the chest, with part of it tipped slightly so that it taps against the left side of the chest.