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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
Women are 50% to 75% more likely than men to experience an adverse drug reaction.
The toxic levels for lithium carbonate are close to the therapeutic levels. Signs of toxicity include fine hand tremor, polyuria, mild thirst, nausea, general discomfort, diarrhea, vomiting, drowsiness, muscular weakness, lack of coordination, ataxia, giddiness, tinnitus, and blurred vision.
Every 10 seconds, a person in the United States goes to the emergency room complaining of head pain. About 1.2 million visits are for acute migraine attacks.
Medication errors are more common among seriously ill patients than with those with minor conditions.