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Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.
A strange skin disease referred to as Morgellons has occurred in the southern United States and in California. Symptoms include slowly healing sores, joint pain, persistent fatigue, and a sensation of things crawling through the skin. Another symptom is strange-looking, threadlike extrusions coming out of the skin.
Drying your hands with a paper towel will reduce the bacterial count on your hands by 45–60%.
By definition, when a medication is administered intravenously, its bioavailability is 100%.
Malaria was not eliminated in the United States until 1951. The term eliminated means that no new cases arise in a country for 3 years.