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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
There used to be a metric calendar, as well as metric clocks. The metric calendar, or "French Republican Calendar" divided the year into 12 months, but each month was divided into three 10-day weeks. Each day had 10 decimal hours. Each hour had 100 decimal minutes. Due to lack of popularity, the metric clocks and calendars were ended in 1795, three years after they had been first marketed.
Throughout history, plants containing cardiac steroids have been used as heart drugs and as poisons (e.g., in arrows used in combat), emetics, and diuretics.
Cancer has been around as long as humankind, but only in the second half of the twentieth century did the number of cancer cases explode.
A seasonal flu vaccine is the best way to reduce the chances you will get seasonal influenza and spread it to others.