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The first oral chemotherapy drug for colon cancer was approved by FDA in 2001.
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In women, pharmacodynamic differences include increased sensitivity to (and increased effectiveness of) beta-blockers, opioids, selective serotonin reuptake inhibitors, and typical antipsychotics.
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Between 1999 and 2012, American adults with high total cholesterol decreased from 18.3% to 12.9%
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Elderly adults are at greatest risk of stroke and myocardial infarction and have the most to gain from prophylaxis. Patients ages 60 to 80 years with blood pressures above 160/90 mm Hg should benefit from antihypertensive treatment.
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According to the FDA, adverse drug events harmed or killed approximately 1,200,000 people in the United States in the year 2015.