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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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More than 34,000 trademarked medication names and more than 10,000 generic medication names are in use in the United States.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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In 1886, William Bates reported on the discovery of a substance produced by the adrenal gland that turned out to be epinephrine (adrenaline). In 1904, this drug was first artificially synthesized by Friedrich Stolz.
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Urine turns bright yellow if larger than normal amounts of certain substances are consumed; one of these substances is asparagus.