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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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In the United States, an estimated 50 million unnecessary antibiotics are prescribed for viral respiratory infections.
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Aspirin is the most widely used drug in the world. It has even been recognized as such by the Guinness Book of World Records.
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More than 30% of American adults, and about 12% of children utilize health care approaches that were developed outside of conventional medicine.