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In ancient Rome, many of the richer people in the population had lead-induced gout. The reason for this is unclear. Lead poisoning has also been linked to madness.
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In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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In the ancient and medieval periods, dysentery killed about ? of all babies before they reach 12 months of age. The disease was transferred through contaminated drinking water, because there was no way to adequately dispose of sewage, which contaminated the water.
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Cancer has been around as long as humankind, but only in the second half of the twentieth century did the number of cancer cases explode.