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The first oral chemotherapy drug for colon cancer was approved by FDA in 2001.
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Though Candida and Aspergillus species are the most common fungal pathogens causing invasive fungal disease in the immunocompromised, infections due to previously uncommon hyaline and dematiaceous filamentous fungi are occurring more often today. Rare fungal infections, once accurately diagnosed, may require surgical debridement, immunotherapy, and newer antifungals used singly or in combination with older antifungals, on a case-by-case basis.
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The ratio of hydrogen atoms to oxygen in water (H2O) is 2:1.
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In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.
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The FDA recognizes 118 routes of administration.