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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
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This year, an estimated 1.4 million Americans will have a new or recurrent heart attack.
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Studies show that systolic blood pressure can be significantly lowered by taking statins. In fact, the higher the patient's baseline blood pressure, the greater the effect of statins on his or her blood pressure.
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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
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The first war in which wide-scale use of anesthetics occurred was the Civil War, and 80% of all wounds were in the extremities.