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Asthma cases in Americans are about 75% higher today than they were in 1980.
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On average, someone in the United States has a stroke about every 40 seconds. This is about 795,000 people per year.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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Sildenafil (Viagra®) has two actions that may be of consequence in patients with heart disease. It can lower the blood pressure, and it can interact with nitrates. It should never be used in patients who are taking nitrates.
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In women, pharmacodynamic differences include increased sensitivity to (and increased effectiveness of) beta-blockers, opioids, selective serotonin reuptake inhibitors, and typical antipsychotics.