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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
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Signs and symptoms of a drug overdose include losing consciousness, fever or sweating, breathing problems, abnormal pulse, and changes in skin color.
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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In the United States, an estimated 50 million unnecessary antibiotics are prescribed for viral respiratory infections.
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Recent studies have shown that the number of medication errors increases in relation to the number of orders that are verified per pharmacist, per work shift.

