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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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Increased intake of vitamin D has been shown to reduce fractures up to 25% in older people.
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Interferon was scarce and expensive until 1980, when the interferon gene was inserted into bacteria using recombinant DNA technology, allowing for mass cultivation and purification from bacterial cultures.
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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The ratio of hydrogen atoms to oxygen in water (H2O) is 2:1.