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Urine turns bright yellow if larger than normal amounts of certain substances are consumed; one of these substances is asparagus.
It is believed that the Incas used anesthesia. Evidence supports the theory that shamans chewed cocoa leaves and drilled holes into the heads of patients (letting evil spirits escape), spitting into the wounds they made. The mixture of cocaine, saliva, and resin numbed the site enough to allow hours of drilling.
In 1864, the first barbiturate (barbituric acid) was synthesized.
After 5 years of being diagnosed with rheumatoid arthritis, one every three patients will no longer be able to work.
The first-known contraceptive was crocodile dung, used in Egypt in 2000 BC. Condoms were also reportedly used, made of animal bladders or intestines.