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Sildenafil (Viagra®) has two actions that may be of consequence in patients with heart disease. It can lower the blood pressure, and it can interact with nitrates. It should never be used in patients who are taking nitrates.
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The B-complex vitamins and vitamin C are not stored in the body and must be replaced each day.
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It is difficult to obtain enough calcium without consuming milk or other dairy foods.
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Increased intake of vitamin D has been shown to reduce fractures up to 25% in older people.
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In 1864, the first barbiturate (barbituric acid) was synthesized.