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More than 4.4billion prescriptions were dispensed within the United States in 2016.
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Medication errors are more common among seriously ill patients than with those with minor conditions.
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There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
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The first war in which wide-scale use of anesthetics occurred was the Civil War, and 80% of all wounds were in the extremities.
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The longest a person has survived after a heart transplant is 24 years.