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Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.
On average, someone in the United States has a stroke about every 40 seconds. This is about 795,000 people per year.
When blood is deoxygenated and flowing back to the heart through the veins, it is dark reddish-blue in color. Blood in the arteries that is oxygenated and flowing out to the body is bright red. Whereas arterial blood comes out in spurts, venous blood flows.
The people with the highest levels of LDL are Mexican American males and non-Hispanic black females.
The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.