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Once thought to have neurofibromatosis, Joseph Merrick (also known as "the elephant man") is now, in retrospect, thought by clinical experts to have had Proteus syndrome. This endocrine disease causes continued and abnormal growth of the bones, muscles, skin, and so on and can become completely debilitating with severe deformities occurring anywhere on the body.
About 100 new prescription or over-the-counter drugs come into the U.S. market every year.
Bacteria have been found alive in a lake buried one half mile under ice in Antarctica.
Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
Illicit drug use costs the United States approximately $181 billion every year.

