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Throughout history, plants containing cardiac steroids have been used as heart drugs and as poisons (e.g., in arrows used in combat), emetics, and diuretics.
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Signs of depression include feeling sad most of the time for 2 weeks or longer; loss of interest in things normally enjoyed; lack of energy; sleep and appetite disturbances; weight changes; feelings of hopelessness, helplessness, or worthlessness; an inability to make decisions; and thoughts of death and suicide.
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Human kidneys will clean about 1 million gallons of blood in an average lifetime.
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By definition, when a medication is administered intravenously, its bioavailability is 100%.
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The first oral chemotherapy drug for colon cancer was approved by FDA in 2001.