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Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.
For pediatric patients, intravenous fluids are the most commonly cited products involved in medication errors that are reported to the USP.
Medications that are definitely not safe to take when breastfeeding include radioactive drugs, antimetabolites, some cancer (chemotherapy) agents, bromocriptine, ergotamine, methotrexate, and cyclosporine.
Women are 50% to 75% more likely than men to experience an adverse drug reaction.
In the United States, there is a birth every 8 seconds, according to the U.S. Census Bureau's Population Clock.