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The use of salicylates dates back 2,500 years to Hippocrates's recommendation of willow bark (from which a salicylate is derived) as an aid to the pains of childbirth. However, overdosage of salicylates can harm body fluids, electrolytes, the CNS, the GI tract, the ears, the lungs, the blood, the liver, and the kidneys and cause coma or death.
More than 4.4billion prescriptions were dispensed within the United States in 2016.
Human kidneys will clean about 1 million gallons of blood in an average lifetime.
Urine turns bright yellow if larger than normal amounts of certain substances are consumed; one of these substances is asparagus.
Long-term mental and physical effects from substance abuse include: paranoia, psychosis, immune deficiencies, and organ damage.