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Coca-Cola originally used coca leaves and caffeine from the African kola nut. It was advertised as a therapeutic agent and "pickerupper." Eventually, its formulation was changed, and the coca leaves were removed because of the effects of regulation on cocaine-related products.
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As of mid-2016, 18.2 million people were receiving advanced retroviral therapy (ART) worldwide. This represents between 43–50% of the 34–39.8 million people living with HIV.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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The first oral chemotherapy drug for colon cancer was approved by FDA in 2001.
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Urine turns bright yellow if larger than normal amounts of certain substances are consumed; one of these substances is asparagus.