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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
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HIV testing reach is still limited. An estimated 40% of people with HIV (more than 14 million) remain undiagnosed and do not know their infection status.
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The first oral chemotherapy drug for colon cancer was approved by FDA in 2001.
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Human kidneys will clean about 1 million gallons of blood in an average lifetime.
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Medication errors are three times higher among children and infants than with adults.