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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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The average office desk has 400 times more bacteria on it than a toilet.
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By definition, when a medication is administered intravenously, its bioavailability is 100%.
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Amphetamine poisoning can cause intravascular coagulation, circulatory collapse, rhabdomyolysis, ischemic colitis, acute psychosis, hyperthermia, respiratory distress syndrome, and pericarditis.
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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.