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ACTH levels are normally highest in the early morning (between 6 and 8 A.M.) and lowest in the evening (between 6 and 11 P.M.). Therefore, a doctor who suspects abnormal levels looks for low ACTH in the morning and high ACTH in the evening.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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The ratio of hydrogen atoms to oxygen in water (H2O) is 2:1.
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In women, pharmacodynamic differences include increased sensitivity to (and increased effectiveness of) beta-blockers, opioids, selective serotonin reuptake inhibitors, and typical antipsychotics.
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Multiple experimental evidences have confirmed that at the molecular level, cancer is caused by lesions in cellular DNA.