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There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
After a vasectomy, it takes about 12 ejaculations to clear out sperm that were already beyond the blocked area.
The human body produces and destroys 15 million blood cells every second.
Approximately 25% of all reported medication errors result from some kind of name confusion.
Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.