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In the United States, an estimated 50 million unnecessary antibiotics are prescribed for viral respiratory infections.
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Long-term mental and physical effects from substance abuse include: paranoia, psychosis, immune deficiencies, and organ damage.
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Of the estimated 2 million heroin users in the United States, 600,000–800,000 are considered hardcore addicts. Heroin addiction is considered to be one of the hardest addictions to recover from.
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In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.