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It is difficult to obtain enough calcium without consuming milk or other dairy foods.
Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
Cancer has been around as long as humankind, but only in the second half of the twentieth century did the number of cancer cases explode.
In ancient Rome, many of the richer people in the population had lead-induced gout. The reason for this is unclear. Lead poisoning has also been linked to madness.