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Although puberty usually occurs in the early teenage years, the world's youngest parents were two Chinese children who had their first baby when they were 8 and 9 years of age.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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As the western states of America were settled, pioneers often had to drink rancid water from ponds and other sources. This often resulted in chronic diarrhea, causing many cases of dehydration and death that could have been avoided if clean water had been available.
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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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In the United States, an estimated 50 million unnecessary antibiotics are prescribed for viral respiratory infections.