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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
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The Romans did not use numerals to indicate fractions but instead used words to indicate parts of a whole.
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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
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About 3% of all pregnant women will give birth to twins, which is an increase in rate of nearly 60% since the early 1980s.
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Thyroid conditions cause a higher risk of fibromyalgia and chronic fatigue syndrome.