Instructions: Refer to the data below to answer the following question(s).
Porcine dynorphin is a neuropeptide having 17 amino acid residues. Its structure is shown below.
Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln
Refer to instructions. What fragments would result if dynorphin were cleaved by trypsin?
Question 2Write the equation for the reaction, using methanol (CH
3OH), that would render the carboxyl group of alanine unreactive.
Question 3Instructions: Consider the following structure. Based on this structure answer the following question(s).
Refer to instructions. How many other peptides could be formed from this same combination of amino acids?
a.
3
b.
6
c.
9
d.
12
Question 4Instructions: Consider the following structure. Based on this structure answer the following question(s).
Refer to instructions. Name the peptide using both the three-letter and one-letter codes.
Question 5Instructions: Consider the following structure. Based on this structure answer the following question(s).
Refer to instructions. Circle the peptide bonds.
Question 6Instructions: Consider the following structure. Based on this structure answer the following question(s).
Refer to instructions. Identify the C-terminal amino acid and the N-terminal amino acid.
Question 7Instructions: Refer to the data below to answer the following question.
Amino Acid
Isoelectric point
Arginine
10.76
Glutamic Acid
3.22
Tryptophan
5.89
Define isoelectric point.