The product of an aldol condensation reaction is generally favored if
a. an aldehyde is disubstituted.
b. a ketone is disubstituted.
c. an aldehyde has no alpha substituents.
d. substituents near the carbonyl are large.
Question 2
Which of the following does not characterize carbonyl condensation reactions?
a. rare in biological systems
b. form new carbon-to-carbon bonds
c. enolate ion can act as a nucleophile
d. an -hydrogen required for an aldol condensation
e. All of these characterize carbonyl condensation reactions.
Reaction coordinate diagram
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Nucleophilic addition reaction of aldehydes and ketones
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