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In 1885, the Lloyd Manufacturing Company of Albany, New York, promoted and sold "Cocaine Toothache Drops" at 15 cents per bottle! In 1914, the Harrison Narcotic Act brought the sale and distribution of this drug under federal control.
Signs of depression include feeling sad most of the time for 2 weeks or longer; loss of interest in things normally enjoyed; lack of energy; sleep and appetite disturbances; weight changes; feelings of hopelessness, helplessness, or worthlessness; an inability to make decisions; and thoughts of death and suicide.
The FDA recognizes 118 routes of administration.
For pediatric patients, intravenous fluids are the most commonly cited products involved in medication errors that are reported to the USP.
More than 34,000 trademarked medication names and more than 10,000 generic medication names are in use in the United States.