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In 1864, the first barbiturate (barbituric acid) was synthesized.
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The effects of organophosphate poisoning are referred to by using the abbreviations “SLUD” or “SLUDGE,” It stands for: salivation, lacrimation, urination, defecation, GI upset, and emesis.
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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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Blood is approximately twice as thick as water because of the cells and other components found in it.
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In women, pharmacodynamic differences include increased sensitivity to (and increased effectiveness of) beta-blockers, opioids, selective serotonin reuptake inhibitors, and typical antipsychotics.