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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
Certain rare plants containing cyanide include apricot pits and a type of potato called cassava. Fortunately, only chronic or massive ingestion of any of these plants can lead to serious poisoning.
The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
More than nineteen million Americans carry the factor V gene that causes blood clots, pulmonary embolism, and heart disease.
According to the FDA, adverse drug events harmed or killed approximately 1,200,000 people in the United States in the year 2015.