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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
Blood in the urine can be a sign of a kidney stone, glomerulonephritis, or other kidney problems.
When blood is exposed to air, it clots. Heparin allows the blood to come in direct contact with air without clotting.
Pubic lice (crabs) are usually spread through sexual contact. You cannot catch them by using a public toilet.
Warfarin was developed as a consequence of the study of a strange bleeding disorder that suddenly occurred in cattle on the northern prairies of the United States in the early 1900s.