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The first monoclonal antibodies were made exclusively from mouse cells. Some are now fully human, which means they are likely to be safer and may be more effective than older monoclonal antibodies.
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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
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Blood in the urine can be a sign of a kidney stone, glomerulonephritis, or other kidney problems.
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When blood is exposed to air, it clots. Heparin allows the blood to come in direct contact with air without clotting.
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In 1835 it was discovered that a disease of silkworms known as muscardine could be transferred from one silkworm to another, and was caused by a fungus.