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In 1864, the first barbiturate (barbituric acid) was synthesized.
The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
Bacteria have been found alive in a lake buried one half mile under ice in Antarctica.
Sildenafil (Viagra®) has two actions that may be of consequence in patients with heart disease. It can lower the blood pressure, and it can interact with nitrates. It should never be used in patients who are taking nitrates.
Signs of depression include feeling sad most of the time for 2 weeks or longer; loss of interest in things normally enjoyed; lack of energy; sleep and appetite disturbances; weight changes; feelings of hopelessness, helplessness, or worthlessness; an inability to make decisions; and thoughts of death and suicide.