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In ancient Rome, many of the richer people in the population had lead-induced gout. The reason for this is unclear. Lead poisoning has also been linked to madness.
More than 150,000 Americans killed by cardiovascular disease are younger than the age of 65 years.
An identified risk factor for osteoporosis is the intake of excessive amounts of vitamin A. Dietary intake of approximately double the recommended daily amount of vitamin A, by women, has been shown to reduce bone mineral density and increase the chances for hip fractures compared with women who consumed the recommended daily amount (or less) of vitamin A.
Cyanide works by making the human body unable to use oxygen.
In 1844, Charles Goodyear obtained the first patent for a rubber condom.