Which of the following supports the notion that the prefrontal ...

[gonzo233]

Which of the following supports the notion that the prefrontal cortex is related to the negative symptoms of schizophrenia?
 
  A) Schizophrenic patients show a greater number of neurons within the gray matter of the frontal cortex.
  B) Schizophrenic patients show greater activity of the frontal cortex than do controls.
  C) Schizophrenic patients do poorly on neuropsychological tests that are sensitive to damage of the prefrontal cortex.
  D) MRI studies indicate abnormalities within the parietal cortex of schizophrenics.
  E) MRI studies indicate abnormalities within the temporal cortex of schizophrenics.

Question 2

________ reverses the positive, negative, and cognitive symptoms by schizophrenia by acting as a ________ in the prefrontal cortex and nucleus accumbens.
 
  A) L-DOPA; competitive antagonist
  B) Aripiprazole; partial agonist
  C) Reserpine; monamine agonist
  D) Aripiprazole; reuptake inhibitor
  E) Amphetamine; reuptake inhibitor

[katkat_flores]

Answer to Question 1

Answer: C
Rationale: The fact that schizophrenic patients do poorly on neuropsychological tests that are sensitive to damage of the prefrontal cortex supports the notion that the prefrontal cortex is related to the negative symptoms of schizophrenia.

Answer to Question 2

Answer: B
Rationale: Aripiprazole reverses the positive, negative, and cognitive symptoms by schizophrenia by acting as a partial agonist in the prefrontal cortex and nucleus accumbens.