This topic contains a solution. Click here to go to the answer

Author Question: Explain what is meant by a place cell, and discuss the role of these cells in spatial memory. ... (Read 55 times)

Shelles

  • Hero Member
  • *****
  • Posts: 582
Explain what is meant by a place cell, and discuss the role of these cells in spatial memory.
 
  What will be an ideal response?

Question 2

Describe the physical changes that occur in the synapses of the hippocampus that may provide a physiological basis for long-term potentiation (LTP).
 
  What will be an ideal response?



Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

Galvarado142

  • Sr. Member
  • ****
  • Posts: 348
Answer to Question 1

Answer: The ability to navigate requires an intact hippocampus. H.M. has difficulties in spatial navigation. The firing rate of individual hippocampal cells was a function of the spatial location of the rat as it wandered around a maze. The external cues of the environment can control the firing rate of hippocampal cells, particularly of cells in the dorsal hippocampus (a key region for spatial navigation). The entorhinal cortex, which is an important input zone for the hippocampus, is also important for spatial navigation.

Answer to Question 2

Answer: LTP is an increased EPSP recorded from dentate cells to a single electrical pulse when that pulse was preceded by high-frequency electrical stimulation of axons that connect with the dentate gyrus cells. There is evidence that more glutamate may be released from the presynaptic terminal button (perhaps due to the influence of nitric oxide from the postsynaptic cell). On the postsynaptic side, LTP is accompanied by physical reorganization of the dendrite, which includes the insertion of AMPA receptors into the dendrite (more sensitivity to glutamate) and the formation of new dendritic spines, which would serve to increase the postsynaptic response to glutamate. Longer term potentiation involves changes in protein synthesis, in particular that of PKM-zeta.




Shelles

  • Member
  • Posts: 582
Reply 2 on: Jun 22, 2018
YES! Correct, THANKS for helping me on my review


dantucker

  • Member
  • Posts: 346
Reply 3 on: Yesterday
Thanks for the timely response, appreciate it

 

Did you know?

There are more sensory neurons in the tongue than in any other part of the body.

Did you know?

To combat osteoporosis, changes in lifestyle and diet are recommended. At-risk patients should include 1,200 to 1,500 mg of calcium daily either via dietary means or with supplements.

Did you know?

Though “Krazy Glue” or “Super Glue” has the ability to seal small wounds, it is not recommended for this purpose since it contains many substances that should not enter the body through the skin, and may be harmful.

Did you know?

Common abbreviations that cause medication errors include U (unit), mg (milligram), QD (every day), SC (subcutaneous), TIW (three times per week), D/C (discharge or discontinue), HS (at bedtime or "hours of sleep"), cc (cubic centimeters), and AU (each ear).

Did you know?

Approximately 70% of expectant mothers report experiencing some symptoms of morning sickness during the first trimester of pregnancy.

For a complete list of videos, visit our video library