This topic contains a solution. Click here to go to the answer

Author Question: Explain what is meant by a place cell, and discuss the role of these cells in spatial memory. ... (Read 51 times)

Shelles

  • Hero Member
  • *****
  • Posts: 582
Explain what is meant by a place cell, and discuss the role of these cells in spatial memory.
 
  What will be an ideal response?

Question 2

Describe the physical changes that occur in the synapses of the hippocampus that may provide a physiological basis for long-term potentiation (LTP).
 
  What will be an ideal response?



Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

Galvarado142

  • Sr. Member
  • ****
  • Posts: 348
Answer to Question 1

Answer: The ability to navigate requires an intact hippocampus. H.M. has difficulties in spatial navigation. The firing rate of individual hippocampal cells was a function of the spatial location of the rat as it wandered around a maze. The external cues of the environment can control the firing rate of hippocampal cells, particularly of cells in the dorsal hippocampus (a key region for spatial navigation). The entorhinal cortex, which is an important input zone for the hippocampus, is also important for spatial navigation.

Answer to Question 2

Answer: LTP is an increased EPSP recorded from dentate cells to a single electrical pulse when that pulse was preceded by high-frequency electrical stimulation of axons that connect with the dentate gyrus cells. There is evidence that more glutamate may be released from the presynaptic terminal button (perhaps due to the influence of nitric oxide from the postsynaptic cell). On the postsynaptic side, LTP is accompanied by physical reorganization of the dendrite, which includes the insertion of AMPA receptors into the dendrite (more sensitivity to glutamate) and the formation of new dendritic spines, which would serve to increase the postsynaptic response to glutamate. Longer term potentiation involves changes in protein synthesis, in particular that of PKM-zeta.




Shelles

  • Member
  • Posts: 582
Reply 2 on: Jun 22, 2018
YES! Correct, THANKS for helping me on my review


LVPMS

  • Member
  • Posts: 323
Reply 3 on: Yesterday
Wow, this really help

 

Did you know?

Patients who cannot swallow may receive nutrition via a parenteral route—usually, a catheter is inserted through the chest into a large vein going into the heart.

Did you know?

Most women experience menopause in their 50s. However, in 1994, an Italian woman gave birth to a baby boy when she was 61 years old.

Did you know?

Interferon was scarce and expensive until 1980, when the interferon gene was inserted into bacteria using recombinant DNA technology, allowing for mass cultivation and purification from bacterial cultures.

Did you know?

The Romans did not use numerals to indicate fractions but instead used words to indicate parts of a whole.

Did you know?

Street names for barbiturates include reds, red devils, yellow jackets, blue heavens, Christmas trees, and rainbows. They are commonly referred to as downers.

For a complete list of videos, visit our video library