This topic contains a solution. Click here to go to the answer

Author Question: Explain what is meant by a place cell, and discuss the role of these cells in spatial memory. ... (Read 52 times)

Shelles

  • Hero Member
  • *****
  • Posts: 582
Explain what is meant by a place cell, and discuss the role of these cells in spatial memory.
 
  What will be an ideal response?

Question 2

Describe the physical changes that occur in the synapses of the hippocampus that may provide a physiological basis for long-term potentiation (LTP).
 
  What will be an ideal response?



Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

Galvarado142

  • Sr. Member
  • ****
  • Posts: 348
Answer to Question 1

Answer: The ability to navigate requires an intact hippocampus. H.M. has difficulties in spatial navigation. The firing rate of individual hippocampal cells was a function of the spatial location of the rat as it wandered around a maze. The external cues of the environment can control the firing rate of hippocampal cells, particularly of cells in the dorsal hippocampus (a key region for spatial navigation). The entorhinal cortex, which is an important input zone for the hippocampus, is also important for spatial navigation.

Answer to Question 2

Answer: LTP is an increased EPSP recorded from dentate cells to a single electrical pulse when that pulse was preceded by high-frequency electrical stimulation of axons that connect with the dentate gyrus cells. There is evidence that more glutamate may be released from the presynaptic terminal button (perhaps due to the influence of nitric oxide from the postsynaptic cell). On the postsynaptic side, LTP is accompanied by physical reorganization of the dendrite, which includes the insertion of AMPA receptors into the dendrite (more sensitivity to glutamate) and the formation of new dendritic spines, which would serve to increase the postsynaptic response to glutamate. Longer term potentiation involves changes in protein synthesis, in particular that of PKM-zeta.




Shelles

  • Member
  • Posts: 582
Reply 2 on: Jun 22, 2018
Wow, this really help


robbielu01

  • Member
  • Posts: 336
Reply 3 on: Yesterday
Great answer, keep it coming :)

 

Did you know?

Fungal nail infections account for up to 30% of all skin infections. They affect 5% of the general population—mostly people over the age of 70.

Did you know?

The average office desk has 400 times more bacteria on it than a toilet.

Did you know?

Astigmatism is the most common vision problem. It may accompany nearsightedness or farsightedness. It is usually caused by an irregularly shaped cornea, but sometimes it is the result of an irregularly shaped lens. Either type can be corrected by eyeglasses, contact lenses, or refractive surgery.

Did you know?

Inotropic therapy does not have a role in the treatment of most heart failure patients. These drugs can make patients feel and function better but usually do not lengthen the predicted length of their lives.

Did you know?

Adult head lice are gray, about ? inch long, and often have a tiny dot on their backs. A female can lay between 50 and 150 eggs within the several weeks that she is alive. They feed on human blood.

For a complete list of videos, visit our video library