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By definition, when a medication is administered intravenously, its bioavailability is 100%.
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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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Addicts to opiates often avoid treatment because they are afraid of withdrawal. Though unpleasant, with proper management, withdrawal is rarely fatal and passes relatively quickly.
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In 2010, opiate painkllers, such as morphine, OxyContin®, and Vicodin®, were tied to almost 60% of drug overdose deaths.
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Russia has the highest death rate from cardiovascular disease followed by the Ukraine, Romania, Hungary, and Poland.