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The most common treatment options for addiction include psychotherapy, support groups, and individual counseling.

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It is believed that the Incas used anesthesia. Evidence supports the theory that shamans chewed cocoa leaves and drilled holes into the heads of patients (letting evil spirits escape), spitting into the wounds they made. The mixture of cocaine, saliva, and resin numbed the site enough to allow hours of drilling.

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Cyanide works by making the human body unable to use oxygen.

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In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.

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Of the estimated 2 million heroin users in the United States, 600,000–800,000 are considered hardcore addicts. Heroin addiction is considered to be one of the hardest addictions to recover from.

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