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Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.

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Common abbreviations that cause medication errors include U (unit), mg (milligram), QD (every day), SC (subcutaneous), TIW (three times per week), D/C (discharge or discontinue), HS (at bedtime or "hours of sleep"), cc (cubic centimeters), and AU (each ear).

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Between 1999 and 2012, American adults with high total cholesterol decreased from 18.3% to 12.9%

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Though Candida and Aspergillus species are the most common fungal pathogens causing invasive fungal disease in the immunocompromised, infections due to previously uncommon hyaline and dematiaceous filamentous fungi are occurring more often today. Rare fungal infections, once accurately diagnosed, may require surgical debridement, immunotherapy, and newer antifungals used singly or in combination with older antifungals, on a case-by-case basis.

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Illicit drug use costs the United States approximately $181 billion every year.

Graphic display of hypothetical results of a predator removal experiment. Graphic display of hypothetical results of a predator removal experiment.
Pap smear. Cells of the cervix (shown in the center) change in appearance as they progress through Pap smear. Cells of the cervix (shown in the center) change in appearance as they progress through
Activity versus specific activity Activity versus specific activity
Model for evidence-based clinical decision making. Model for evidence-based clinical decision making.
Likelihood of Developing Type 2 Diabetes Mellitus Based on BMI Likelihood of Developing Type 2 Diabetes Mellitus Based on BMI
Cost = $99.49; Rate of markup based on cost = 32%. Find the markup and selling price. Cost = $99.49; Rate of markup based on cost = 32%. Find the markup and selling price.
Video: Carbohydrate Metabolism: Introduction to renal processes and filtrate formation and composition

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