Author Question: Explain why chemical stimulation is sometimes preferred over electrical stimulation. What will be ... (Read 111 times)

jon_i

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Explain why chemical stimulation is sometimes preferred over electrical stimulation.
 
  What will be an ideal response?

Question 2

Explain how autoradiography can be used to measure the activity of brain cells.
 
  What will be an ideal response?



lkoler

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Answer to Question 1

Answer: Chemical stimulation can be used to excite cell bodies rather than both cell bodies and axons of passage.

Answer to Question 2

Answer: Brain cells require glucose as fuel for activity. 2-DG , like glucose, is taken up into neurons, but cannot be used for energy. If a radioactive version of 2-DG is injected into an animal, radioactive 2-DG molecules will accumulate in brain as a function of the relative activity of those cells. Autoradiography will reveal the presence of radioactive molecules in the brain, with a more intense signal in regions that were more active, and a less intense signal in less active regions.



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