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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
Throughout history, plants containing cardiac steroids have been used as heart drugs and as poisons (e.g., in arrows used in combat), emetics, and diuretics.
Everyone has one nostril that is larger than the other.
People about to have surgery must tell their health care providers about all supplements they take.
The U.S. Preventive Services Task Force recommends that all women age 65 years of age or older should be screened with bone densitometry.