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Acetaminophen (Tylenol) in overdose can seriously damage the liver. It should never be taken by people who use alcohol heavily; it can result in severe liver damage and even a condition requiring a liver transplant.
People with high total cholesterol have about two times the risk for heart disease as people with ideal levels.
Medications that are definitely not safe to take when breastfeeding include radioactive drugs, antimetabolites, some cancer (chemotherapy) agents, bromocriptine, ergotamine, methotrexate, and cyclosporine.
More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
According to the FDA, adverse drug events harmed or killed approximately 1,200,000 people in the United States in the year 2015.