Imaging studies indicate that greater consumption of cocaine produces
a. increased activation of the orbitofrontal cortex.
b. increased blood flow in the prefrontal cortex.
c. increased blood flow in the anterior cingulate cortex.
d. decreased activation of the medial prefrontal cortex.
e. decreased dopamine production in the nucleus accumbens.
Question 2
A rat is trained to self-administer cocaine. Saline is substituted for the cocaine solution, which results in extinction of responding. In this situation, the capacity for a free shot of cocaine to reinstate responding for cocaine can be blocked by
a. injection of AMPA into the ventromedial prefrontal cortex.
b. injection of a dopamine agonist into the nucleus accumbens.
c. glutamate induced activation of the ventral tegmental area.
d. injection of a dopamine agonist into the prefrontal cortex.
e. injection of glycine into the ventromedial prefrontal cortex.
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