Which of the following most correctly describes the sequence of toxic events that occur in brain during a stroke?
a. increased blood flow > activation of NA+/K+ transporters > membrane hyperpolarization > GABA release > excessive accumulation of extracellular CA++
b. reduced blood flow > inactivation of Na+/K+ transporters > membrane depolarization > glutamate release > excessive accumulation of intracellular CA++
c. reduced blood flow > activation of Na+/K+ transporters > membrane hyperpolarization > DA release > excessive accumulation of intracellular CL-
d. reduced blood flow > inactivation of Na+/K+ transporters > membrane hyperpolarization > GABA release > excessive accumulation of intracellular CA++
e. increased blood flow > reduced accumulation of extracellular CA++ > membrane hyperpolarization > GABA release
Question 2
A 50-year-old man has experienced a major stroke caused by a thrombus that occluded brain blood vessels. To prevent the occurrence of another stroke, his physicians would most likely
a. administer an anticoagulant.
b. administer drugs that lower blood pressure.
c. cut out the embolus using invasive surgery.
d. use deep brain stimulation to facilitate neuron regrowth.
e. administer massive doses of antibiotics.
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An insertion sequence (IS), shown in purple