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Throughout history, plants containing cardiac steroids have been used as heart drugs and as poisons (e.g., in arrows used in combat), emetics, and diuretics.
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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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Addicts to opiates often avoid treatment because they are afraid of withdrawal. Though unpleasant, with proper management, withdrawal is rarely fatal and passes relatively quickly.
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Cancer has been around as long as humankind, but only in the second half of the twentieth century did the number of cancer cases explode.
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After a vasectomy, it takes about 12 ejaculations to clear out sperm that were already beyond the blocked area.